Ms. Kazaguruma is a recurring character appearing in High School Years and Forever Sophomores. Tom and co. usually had her for a substitute in Science class. She first appeared in "The New Diode".
Ms. Kazaguruma is a kind and helpful teacher. She often helps Tom and co. whenever they are confused about a certain Science subject, and often gets upset with other students, such as Eddy or Nathan, whenever they misbehave. In High School Years, she takes Ms. Diode's place as the helper teacher in Biology after she temporarily left to get surgery. This went on for most of Season 24, up until the start of Season 25. In Forever Sophomores, Ms. Kazaguruma returns to take the place of Mrs. Parson after Ms. Kinzoku left in Animas Extravaganza, and Ms. Johnson announcing that she wasn't returning that school year.
Ms. Kazaguruma has fair skin, brown eyes, and short dark brown hair with a black tint. She also wears a pair of glasses. Her outfits vary throughout the series, but she is mostly seen in 2 outfits. In High School Years, she wore a red short-sleeved blouse with an orange floral pattern, black trousers, and black dress shoes. In Forever Sophomores, She wears a purple blouse with greenish-brown trousers and the same shoes.